Magaldrate Gels and Powders

The antacid effectiveness of magaldrate can be used to treat peptic ulcers because it neutralizes gastric acid very quickly while buffering the pH even in presence of proteins and pepsin.

Product Name

Description

% Assay

Density (g/mL)

7000

Crystalline powder, USP, Ph. Eur.

90.0-105.0

0.6-0.9

Magaldrate (Al5Mg10(OH)31(SO4)2,xH20) is a basic aluminum and magnesium compound possessing a layer structure connected by water and sulfate bridges. It is crystalline by nature. This unique crystal lattice structure results in its high reactivity. The antacid effectiveness of magaldrate can be used to treat peptic ulcers because it neutralizes gastric acid very quickly while buffering the pH (keeping it between 5 and 6) even in the presence of proteins and pepsin.

Magaldrate can also adsorb large quantities of bile acids, which prevents these acids from attacking the mucous membranes. Magaldrate is a highly reactive antacid designed for formulation of suspensions and tablets. The gel is available as 10% or 20% suspension. We offer a powder form as well.

 

Product Name

% Magaldrate Assay

% Al(OH)3**

% Mg(OH)2**

Viscosity*

10% Magaldrate Gel

9.8-10.5

32.1-45.9

49.2-66.6

50-100 mPas, as is, Haake Viscometer

20% Magaldrate Gel

20.0-23.0

32.1-45.9

49.2-66.6

50-150 mPas as-is, Haake Viscometer

* Details of Viscometer relating to type and speed is included in the Typical Product Properties located in Related Resources section

** On a 100% Magaldrate basis

Related Applications

Ingredients for Antacids and Laxatives

Ingredients for Antacids and Laxatives

Antacid suspensions can be made from viscous pastes, pumpable gels, powders (preferably micronized) or preformulated products. Antacid tablets and Laxative suspensions can be made from powders, directly compressible (DC) ingredients or DC preformulated products.

Related Resources

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