Actimask™ Acetaminophen
Taste-Masked Acetaminophen for Patient-Friendly Dosage Forms.
Making patients better - without the bitter
Actimask Acetaminophen is SPI Pharma’s advanced taste-masking solution for acetaminophen or paracetamol (APAP), engineered to deliver a pleasant mouthfeel and high API loading - ideal for chewables, orally disintegrating tablets (ODTs), sachets, and stick packs. Designed to improve patient compliance and streamline formulation development, Actimask is the key to making patients better without the bitter.
- Effectively masks bitter taste to improve patient adherence. Actimask Acetaminophen uses a proprietary aqueous gelatin coating to create a physical barrier that prevents taste detection in the oral cavity.
- High API assay (~94%) allows for smaller, more manageable tablets - a major advantage over traditional taste-masked materials with lower drug load.
- Flexible formulation options suitable for pediatric and adult populations, and easily incorporated into chewables, ODTs, and stick pack formats.
Why choose Actimask Acetaminophen?
- Uniform hydrogel coating provides smooth non-gritty mouthfeel which is easy to swallow
- Excellent flow and compressibility (Carr's Index ~13), ideal for direct compression
- Regulatory compliance for global formulations
- Solvent-free manufacturing process with operational efficiency and ease of scale-up
Typical Properties
| Attribute | Actimask Acetaminophen |
|---|---|
| Description | White to off-white granules |
| Average Assay (%) | ~94% |
| Dissolution (%) | ≥ 95% in 30 minutes (Q = 80%) |
| Mean Particle Size (d50) | ~380 µm |
| Bulk Density (g/mL) | ~0.65 |
| Tapped Density (g/mL) | ~0.75 |
| Carr’s Index | ~13 |
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Find out how Actimask Acetaminophen can transform your next formulation.
