Mannogem™ Mannitols

Mannogem™ Mannitol delivers reliable performance and excellent mouthfeel for a range of dosage forms.

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Nitrosamines Testing

Mannogem™ Mannitols have been evaluated for nitrites using highly sensitive analytical methods, with results reported as not detected at a limit of detection of <10 ppb. This testing reflects SPI Pharma’s ongoing commitment to product quality, transparency, and alignment with evolving regulatory expectations.

Nitrosamine Statement_Mannogem

Why Formulators Choose Mannogem™ Mannitol

Your teams innovate every day to design dosage forms that meet both regulatory and patient expectations. Choosing the right excipient shouldn’t slow that process down. Mannogem™ Mannitol is a fully compendial excipient that streamlines development, increases manufacturing efficiency, and supports exceptional patient‑friendly dosage forms—now complemented by our enhanced Mannogem™ XL Series for even greater performance across challenging formulations.

Boost Productivity & Operational Efficiency

Faster throughput enabled by direct compression (DC) grades optimized for high-speed tableting
Low sensitivity to press speed supports consistent tablet quality across a wide range of dwell times
High binding capacity delivers robust, stable tablets—even at lower compression forces

Enhanced Formulation Performance

Low hygroscopicity helps protect moisture‑sensitive actives and supports improved shelf life
Excellent mechanical properties suitable for a wide range of solid dosage forms

Exceptional Patient Experience

Smooth, creamy mouthfeel for pleasant administration
Fast dissolution supports rapid disintegration and improved palatability
Ideal for chewable tablets, ODTs, and other patient‑focused formats

Innovation-Ready Excipient for Modern Dosage Forms

Portable, convenient, patient‑friendly formats
Novel or challenging formulations requiring stability and robust binding
Advanced delivery technologies that demand consistent performance

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Explore the Mannogem™ XL Series

Mannogem™ XL Series

A superhero‑strength mannitol series engineered to deliver stronger tablets, faster disintegration, and simpler formulations.

Mannogem™ Selection Guide

Having trouble choosing the right product for your formulation? We got your covered!