Adding Value to Pharmaceutical Products
For over 75 years, we have supplied the pharmaceutical industry with highly engineered products and innovative solutions that improve the formulation and delivery of drug products to meet patient needs. Our functional excipients and active ingredients meet the highest-quality standards possible and can offer customized, cost-effective options for many applications.
We invite you to explore our product offerings. Our global technical team of experts can also help you select the right product to solve your formulation challenge.
SPI Pharma is the global leader in immediate-relief antacid actives. We specialize in aluminum, magnesium, and calcium products, as well as preformulated solutions for the production of antacid suspensions and tablets. All facilities meet cGMP requirements for APIs and finished dosage forms (FDFs), also known as semi-finished drugs. When the product is compendial, it meets or exceeds the appropriate USP and/or EP Pharmacopoeia specifications. With manufacturing locations in the US and France, SPI Pharma provides security of supply at the highest quality standards through dual sourcing. We work to exceed the expectations for each customer, every time.
Directly compressible (DC) calcium carbonate products from SPI Pharma for swallow and chewable tablets have high functionality and create a superior mouthfeel. Calcium carbonate (CaCO3) is a very reactive antacid active which is used alone or in combination with magnesium compounds. It has a crystalline structure and buffering properties.
SPI Pharma offers a wide range of functional excipients that help our customers produce cost-effective, high-quality finished pharmaceutical and nutritional products. Our highly engineered materials are manufactured in dedicated pharmaceutical facilities and meet the quality standards set for active pharmaceutical ingredients (APIs). Through our process knowledge and formulation expertise we have the ability to support all our customers' applications, including swallow tablets, chewable, soft chew, lozenges, orally disintegrating, and soft gel dosage forms.
SPI Pharma offers the industry’s most innovative formulations of new orally disintegrating tablets and powder products. With the optimal combination of high-quality ingredients and unparalleled expertise, we can solve even the most challenging formulation problems.
Our full spectrum of ODT products, services, and technologies support every stage of your product life cycle. Our fully formulated and optimized Pharmaburst® 500 system for ODT tablets is ready to use, requires no new tableting machinery or additional binders, and is fully supported by our team of formulation experts.
Our Actimask® technology provides an excellent taste barrier and mouth feel without hindering API release and onset of therapeutic relief. By incorporating our taste-masking technology in the development of your product, we can help you increase the chances for success throughout your product life cycle.
SPI Pharma has extensive experience and knowledge of aluminum hydroxide chemistry, with more than 70 years for antacid forms and more than 20 years for VAC gels as a vaccine adjuvant. The result of this expertise is products with a very regular profile in terms of compliance, morphology, particle size distribution, and protein adsorption capacity. SPI has two facilities for the production of its VAC products, one in France and the other in the US. This allows us to ensure security of supply. Both sites produce under cGMP conditions and are regularly audited by the ANSM (French health agency), FDA, and many customers.