SPI Pharma has extensive experience and knowledge of aluminum hydroxide chemistry, with more than 70 years for antacid forms and more than 20 years for VAC gels as a vaccine adjuvant. The result of this expertise is products with a very regular profile in terms of compliance, morphology, particle size distribution, and protein adsorption capacity.
SPI has two facilities for the production of its VAC products, one in France and the other in the US. This allows us to ensure security of supply. Both sites produce under cGMP conditions and are regularly audited by the ANSM (French health agency), FDA, and many customers.
Higher Adsorption Vaccine Adjuvants
The vaccine adjuvant manufacturing process has been optimized to create an adjuvant with a higher protein adsorption capacity, a finer particle size and a narrower pH range. These characteristics make VAC 20 HA a high-performance adjuvant compared to other regular adjuvants.
Standard Vaccine Adjuvants
SPI Pharma offers a range of aluminum hydroxide gel VAC grades for adsorption (pseudo-boehmite form) for use as a vaccine adjuvant. It is used to bind negatively charged antigens.