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Orally Disintegrating Technology (Oral Drug Delivery)

Orally Disintegrating Technology (Oral Drug Delivery)

A Convenient Alternative to Conventional Dosage Forms 

Offering ease of use and convenience, orally disintegrating tablets (ODT) and powders (ODP) have become a preferred dosage form for consumers worldwide for medications in a variety of therapeutic areas. These include traditional over-the-counter (OTC) medicines such as ibuprofen and acetaminophen, well-established prescription drugs such as montelukast and olanzapine, and a variety of other drugs for indications such as sleeplessness, erectile dysfunction, and migraine.

Orally Disintegrating Tablets

An orally disintegrating tablet is a solid-dosage form that disintegrates in the mouth without water in 30 seconds or less, thereby increasing convenience and compliance for a broad range of indications and patient types—including young or elderly patients who may have difficulty swallowing or chewing a conventional tablet, active people who prefer the convenience of taking an ODT that does not require water, and travelers or patients in locations with a limited or unreliable supply of safe water. Orally disintegrating tablets offer a variety of benefits for both patients and manufacturers, making the ODT dosage form a versatile option for many applications.

Benefits of ODT for Patients and Caregivers

  • Allows accurate dosing—no risk of liquid spills
  • Improved patient compliance—easier to take or administer than conventional tablets or liquid forms
  • Ideally suited for non-ambulatory patients and those with difficulty swallowing or chewing
  • More convenient than other dosage forms—easy to swallow, requires no water, and offers quicker onset of therapeutic action for some drugs

Benefits of ODT for Manufacturers

  • A cost-effective way to extend your drug's life cycle—a new ODT formulation can create a branded, differentiated line extension
  • Gain entry into new markets and patient populations
  • Better stability than liquid dosage forms
  • Help meet the growing demand for more patient-friendly and compliant dosage forms

At SPI Pharma, we have many innovative solutions that the industry relies on to develop orally disintegrating tablets (ODT) and powders (ODP). Our functional excipients, taste-masked actives, and comprehensive technical service and support can help you solve even your most challenging formulation problems.

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Related Resources

Related Products

  • Actimask Acetaminophen 80-160mg Orally Disintegrating Tablet-ODT Formulary

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  • Actimask Acetaminophen 125-250mg Orally Disintegrating Tablet-ODT Formulary

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  • Actimask Acetaminophen 500mg Orally Disintegrating Tablet-ODT Formulary

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  • Actimask Ibuprofen 100 mg Taste-Masked IBU Orally Dispersible Powder Formulary

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  • Actimask Acetaminophen 160 mg APAP Orally Dispersible Powder Formulary

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  • Advantol 300 Zinc Soft Chew Tablet Formulary

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  • Advantol 300 Product Sales Bulletin

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  • Comparison of Directly Compressible Drug Delivery Systems for Orally Disintegrating Tablets Application Data Sheet

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  • Prospectus Summary Guide

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  • Capabilities and Dosage Forms

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  • Comparison of Orally Disintegrating Technologies In High Dose Acetaminophen Tablets

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  • Asahi Kasei Press Release

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  • Formulation of Orally Disintegrating Mini Tablets with a Low Dose API- Dextromethorphan HBr

    This application datasheet demonstrates the use of Pharmaburst in the development of orally disintegrating mini tablets.

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    This application datasheet demonstrates the use of Pharmaburst in the development of orally disintegrating mini tablets.

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