4 Reasons to Use Mannitol in Your Formulation

  1. Mannitol is an inert carrier

    Mannitol doesn’t promote acid-base reactions, oxidation, or react with primary amines.

  2. It has high solubility

    Mannitol is highly wettable and can decrease disintegration time, assisting the drug release. It can also improve the solubility of poorly soluble APIs.

  3. Mannitol is non-hygroscopic

    Meaning an increased protection against moisture in formulations, an improved chemical/physical stability of formulation and a protection of hydrolysable/moisture sensitive actives.

  4. Mannitol can be used as a crystal in crystal solid dispersion